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Septicaemic Plague (Yersinia pestis)

Septicaemic Plague Definition:
  • A gram negative septicaemia illness caused by Yersinia pestis.
  • It is one of the 3 main forms of plague.
  • It is usually contracted from the bite of a Yersinia pestis infected flea.
Pathophysiology
  • This plague illness may occur as a complication of bubonic plague and pneumonic plague.
  • Bacteria enter the blood from the lymphatic system, respiratory system or directly.
Symptoms & Complications:
  • Chills
  • Delirium
  • Disseminated intravascular coagulation (DIC)
  • High fever
  • Hypotension
  • Headache
  • Hepatosplenomegaly
  • Lethargy
  • Purple discoloration of skin (patches)
  • Vomiting
  • Seizures (in children)
  • Septic shock
  • Tachycardia
  • ARDS
Prognosis:
  • Almost always fatal.
Differential Diagnosis:
  • Septicemia, other
  • Meningococcemia
Treatment:
  • Intravenous antibiotics - Streptomycin / Gentamicin / Chloramphenicol
  • Circulatory support, dialysis & ventilatory support may be required.
Famous Suffers:

Related Links:

Image credit- Hawaii State Archives - Hawaii plague victim, circa 1899.

Posted by ALCHEssMIST.
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